Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870994 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1MAPK1IDO1NOTUM | |
| SCHEMBL11410050 | 0.81 | KDM4E (0.72) | KDM4EALDH1A1MAPK1NOTUMCHRNA7 | |
| SCHEMBL10653293 | 0.81 | KDM4E (0.72) | KDM4EALDH1A1MAPK1NOTUMCHRNA7 | |
| SCHEMBL6847993 | 0.80 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPK1NOTUMCHRNA7 | |
| SCHEMBL6847991 | 0.80 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPK1NOTUMCHRNA7 | |
| SCHEMBL8828340 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1MAPK1NOTUMCHRNA7 | |
| SCHEMBL8828345 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1MAPK1NOTUMCHRNA7 | |
| SCHEMBL21428687 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMCHRNA7 | |
| SCHEMBL16549641 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMCHRNA7 | |
| SCHEMBL4818138 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | Q6ZSR9, ACSL6, RPS4Y1 | KDM4E 18/4885ALDH1A1 2109/4885MAPK1 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.