Acetic Acid

Acetic Acid

SCHEMBL6871019

CC(=O)[O-].CCCCO[Ti+](OCCCC)OCCCC

nearest known ligand 0.48

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
ATM Q13315 1/20 0.40
CES1 P23141 6/20 0.39
CA1 P00915 2/20 0.39
CES2 O00748 6/20 0.39
TSHR P16473 3/20 0.38
HPGD P15428 1/20 0.38
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL6297796 0.88 TSHR (0.43) ALDH1A1ATMCES1CA1CES2
SCHEMBL13721721 0.85 ALDH1A1 (0.39) ALDH1A1ATMCES1CA1CES2
SCHEMBL21543978 0.83 CA1 (0.39) ALDH1A1ATMCES1CA1CES2
SCHEMBL31340078 0.83 ADRB2 (0.45) ALDH1A1ATMCA1TSHRHPGD
SCHEMBL21544058 0.82 ALDH1A1 (0.37) ALDH1A1ATMCES1CA1TSHR
SCHEMBL7106452 0.81 CA1 (0.36) ALDH1A1ATMCES1CA1CES2
Iodide SCHEMBL9486141 0.80 ADRB2 (0.43) ALDH1A1ATMCA1TSHRHPGD
SCHEMBL7110004 0.79 CA1 (0.39) ALDH1A1ATMCES1CA1CES2
Acetic Acid SCHEMBL1262288 0.76 TSHR (0.54) ALDH1A1ATMCES1CA1CES2
Stearic Acid SCHEMBL31279709 0.75 FABP3 (0.56) CES1CA1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014117225-A1 METAL ORGANIC FRAMEWORKS FALCARO PAOLO (AU) 2014-08-07 WO disclosed
US-6797206-B1 Process of producing a microporous hydrophobic inorganic membrane STICHTING ENERGIEONDERZOEK CENTRUM NEDERLAND (NL) 2004-09-28 US disclosed
EP-1089806-B1 PROCESS OF PRODUCING A MICROPOROUS HYDROPHOBIC INORGANIC MEMBRANE STICHTING ENERGIEONDERZOEKCENT (NL) 2004-06-16 EP disclosed
EP-1089806-A1 PROCESS OF PRODUCING A MICROPOROUS HYDROPHOBIC INORGANIC MEMBRANE Stichting Energieonderzoek Centrum Nederland(ECN) (NL) 2001-04-11 EP disclosed
WO-1999061140-A1 PROCESS OF PRODUCING A MICROPOROUS HYDROPHOBIC INORGANIC MEMBRANE STICHTING ENERGIEONDERZOEK CENTRUM NEDERLAND (NL) 1999-12-02 WO disclosed