Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 11/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.45 |
| ▸ | ACHE | P22303 | 11/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871890 | 1.00 | CNR1 (0.52) | CNR1CNR2MCHR1ADRA2ABCHE | |
| SCHEMBL6868622 | 0.91 | ADRA2A (0.46) | CNR1CNR2MCHR1ADRA2ABCHE | |
| SCHEMBL6868628 | 0.91 | ADRA2A (0.46) | CNR1CNR2MCHR1ADRA2ABCHE | |
| SCHEMBL13792947 | 0.88 | MCHR1 (0.65) | CNR1CNR2MCHR1ADRA2A | |
| SCHEMBL6874888 | 0.83 | MCHR1 (0.49) | MCHR1ADRA2A | |
| SCHEMBL6874892 | 0.83 | MCHR1 (0.49) | MCHR1ADRA2A | |
| SCHEMBL6461772 | 0.81 | MCHR1 (0.52) | MCHR1ADRA2A | |
| SCHEMBL6463779 | 0.81 | MCHR1 (0.52) | MCHR1ADRA2A | |
| SCHEMBL6460482 | 0.80 | CNR1 (0.53) | CNR1CNR2MCHR1ADRA2ACHRM1 | |
| SCHEMBL6460488 | 0.80 | CNR1 (0.53) | CNR1CNR2MCHR1ADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |