Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457298 | 0.89 | KDM4E (0.44) | KDM4EMAPTMCHR1NPY5RADRA2A | |
| SCHEMBL6457315 | 0.89 | KDM4E (0.44) | KDM4EMAPTMCHR1NPY5RADRA2A | |
| SCHEMBL6875428 | 0.86 | MCHR1 (0.43) | KDM4EMCHR1ACACBNPY5RADRA2A | |
| SCHEMBL6875436 | 0.86 | MCHR1 (0.43) | KDM4EMCHR1ACACBNPY5RADRA2A | |
| SCHEMBL6464046 | 0.85 | MCHR1 (0.42) | KDM4EMAPTMCHR1NPY5RADRA2A | |
| SCHEMBL6464055 | 0.85 | MCHR1 (0.42) | KDM4EMAPTMCHR1NPY5RADRA2A | |
| SCHEMBL4034542 | 0.85 | MCHR1 (0.51) | KDM4EMAPTMCHR1NPY5RADRA2A | |
| SCHEMBL4034537 | 0.85 | MCHR1 (0.51) | KDM4EMAPTMCHR1NPY5RADRA2A | |
| SCHEMBL6463399 | 0.84 | MCHR1 (0.44) | KDM4EMCHR1ACACBNPY5RADRA2A | |
| SCHEMBL6463392 | 0.84 | MCHR1 (0.44) | KDM4EMCHR1ACACBNPY5RADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |