Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687881 | 0.90 | PTGER3 (0.40) | FFAR1PTGER3MAPTTP53NPSR1 | |
| SCHEMBL687870 | 0.89 | KMT2A (0.40) | FFAR1KMT2AMAPTP2RX3NPSR1 | |
| SCHEMBL687724 | 0.88 | SMN1; SMN2 (0.36) | FFAR1PTGER3KMT2ANPSR1RXFP1 | |
| SCHEMBL688582 | 0.87 | SMN1; SMN2 (0.39) | FFAR1PTGER3KMT2AKDM4E | |
| SCHEMBL686979 | 0.85 | KMT2A (0.38) | KMT2AMEN1 | |
| SCHEMBL688419 | 0.84 | SMN1; SMN2 (0.35) | FFAR1PTGER3KMT2APPARGP2RX3 | |
| SCHEMBL688331 | 0.83 | SMN1; SMN2 (0.38) | FFAR1PTGER3KMT2ANPSR1RXFP1 | |
| SCHEMBL686761 | 0.82 | SMN1; SMN2 (0.37) | KMT2AMAPTNPSR1RXFP1KDM4E | |
| SCHEMBL687744 | 0.81 | PTGER3 (0.43) | FFAR1PTGER3MAPTTP53NPSR1 | |
| SCHEMBL686627 | 0.81 | SMN1; SMN2 (0.42) | PTGER3KMT2AMAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |