Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872073 | 1.00 | NPY5R (0.45) | NPY5RMCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6874117 | 0.86 | MCHR1 (0.45) | NPY5RMCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6874121 | 0.86 | MCHR1 (0.45) | NPY5RMCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6877871 | 0.86 | NPY5R (0.48) | NPY5RMCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6868742 | 0.84 | MCHR1 (0.48) | NPY5RMCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6875375 | 0.84 | MCHR1 (0.48) | NPY5RMCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6868739 | 0.84 | MCHR1 (0.48) | NPY5RMCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6875379 | 0.84 | MCHR1 (0.48) | NPY5RMCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL13796860 | 0.84 | MCHR1 (0.63) | NPY5RMCHR1ADRA2A | |
| SCHEMBL6868360 | 0.83 | MCHR1 (0.47) | NPY5RMCHR1ADRA2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |