Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAT2A | P31153 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11610757 | 0.84 | NR1I2 (0.58) | MAPTTP53LMNAKDM4EMEN1 | |
| SCHEMBL11636311 | 0.84 | CASR (0.53) | MAPTFNTAFNTBUSP2ALDH1A1 | |
| SCHEMBL11634409 | 0.83 | MAPT (0.47) | MAPTFNTAFNTBLMNAKDM4E | |
| SCHEMBL11159965 | 0.83 | KDM4E (0.49) | MAPTTP53LMNAKDM4ECASP1 | |
| SCHEMBL11609021 | 0.83 | CASR (0.45) | MAPTTP53FNTAFNTBKDM4E | |
| SCHEMBL11601877 | 0.82 | CASR (0.67) | TP53 | |
| SCHEMBL11157753 | 0.82 | MAPT (0.61) | MAPTTP53LMNAKDM4EHSD17B10 | |
| SCHEMBL11607868 | 0.82 | MAPT (0.58) | MAPTTP53LMNAKDM4EMAPK1 | |
| SCHEMBL11608488 | 0.82 | HPGD (0.53) | LMNAKDM4ENPSR1KMT2AHSD17B10 | |
| SCHEMBL11635950 | 0.81 | DHODH (0.45) | MAPTTP53FNTAFNTBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247554-A | ADMINISTERING A QUINAZOLINONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-27 | — | — | US | claimed |
| US-6815543-B1 | METALLOPORPHYRIN IN A NON-REACTIVE APROTIC SOLVENT | WARNER-LAMBERT COMPANY | 2004-11-09 | — | — | US | disclosed |
| CN-1367769-A | Process for catalyzing oxidation of organic compounds | WARNER LAMBERT CO (US) | 2002-09-04 | — | — | CN | disclosed |
| EP-1208069-A1 | PROCESS FOR CATALYZING THE OXIDATION OF ORGANIC COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001010797-A1 | PROCESS FOR CATALYZING THE OXIDATION OF ORGANIC COMPOUNDS | WARNER LAMBERT COMPANY (US) | 2001-02-15 | — | — | WO | disclosed |
| US-4258187-A | REACTING 2-AMINO-BENZOPHENONE DERIVATIVES WITH A HYDROXYLAMINE SALT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4247554-A | ADMINISTERING A QUINAZOLINONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-27 | — | — | US | disclosed |
| EP-0000149-A1 | Process for preparing quinazolinone oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |
| US-4067868-A | Production of quinazolinone compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-01-10 | — | — | US | disclosed |
| US-3953446-A | Process for preparing quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-27 | — | — | US | disclosed |