Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637290 | 0.83 | MAPT (0.46) | DHODHLMNAMAPTTP53 | |
| SCHEMBL11610757 | 0.82 | NR1I2 (0.58) | DHODHCASRNR1I2EGFRADRA2A | |
| SCHEMBL6872385 | 0.81 | MAPT (0.53) | ALDH1A1KDM4ELMNAFNTAFNTB | |
| SCHEMBL11609021 | 0.81 | CASR (0.45) | CASRNR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11608488 | 0.79 | HPGD (0.53) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11166830 | 0.78 | MAPT (0.43) | LMNAMAPTTP53 | |
| SCHEMBL11602843 | 0.78 | CASR (0.68) | CASRALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL11635887 | 0.77 | NPBWR1 (0.44) | CASRNR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11608433 | 0.77 | FNTA (0.48) | DHODHCASRNR1I2EGFRADRA2A | |
| SCHEMBL11606364 | 0.76 | L3MBTL1 (0.67) | EGFRALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |