Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609021 | 0.84 | CASR (0.45) | NR1I2ADORA3EGFRADRA2ATBXA2R | |
| SCHEMBL6872385 | 0.84 | MAPT (0.53) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL11608488 | 0.83 | HPGD (0.53) | NR1I2ADORA3EGFRADRA2ATBXA2R | |
| SCHEMBL11634049 | 0.82 | NR1I2 (0.54) | NR1I2ADORA3EGFRADRA2ATBXA2R | |
| SCHEMBL11635950 | 0.82 | DHODH (0.45) | NR1I2ADORA3EGFRADRA2ATBXA2R | |
| SCHEMBL11602843 | 0.82 | CASR (0.68) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL11635887 | 0.81 | NPBWR1 (0.44) | NR1I2ADORA3EGFRADRA2ATBXA2R | |
| SCHEMBL11608433 | 0.81 | FNTA (0.48) | NR1I2ADORA3EGFRADRA2ATBXA2R | |
| SCHEMBL11606364 | 0.80 | L3MBTL1 (0.67) | EGFRKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL3523185 | 0.78 | L3MBTL1 (0.46) | NR1I2ADORA3EGFRADRA2ATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067868-A | Production of quinazolinone compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-01-10 | — | — | US | disclosed |
| US-3953446-A | Process for preparing quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-27 | — | — | US | disclosed |