SCHEMBL687243

SCHEMBL687243

COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.47
BLM P54132 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
BTN3A1 O00481 4/20 0.43
MVD P53602 3/20 0.33
FNTA P49354 3/20 0.32
PGGT1B P53609 2/20 0.32
FNTB P49356 1/20 0.32
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16855741 1.00 FDPS (0.47) FDPSBLMTDP1BTN3A1MVD
SCHEMBL412533 1.00 FDPS (0.47) FDPSBLMTDP1BTN3A1MVD
Ammonia Solution, Strong SCHEMBL28227868 0.97 FDPS (0.45) FDPSBLMTDP1BTN3A1MVD
SCHEMBL9580811 0.97 FDPS (0.45) FDPSBLMTDP1BTN3A1MVD
SCHEMBL10862597 0.97 FDPS (0.45) FDPSBLMTDP1BTN3A1MVD
Ammonia Solution, Strong SCHEMBL28227867 0.97 FDPS (0.45) FDPSBLMTDP1BTN3A1MVD
SCHEMBL19387807 0.94 FDPS (0.53) FDPSBLMTDP1BTN3A1MVD
SCHEMBL889928 0.94 FDPS (0.53) FDPSBLMTDP1BTN3A1MVD
Ammonia Solution, Strong SCHEMBL28569612 0.92 FDPS (0.50) FDPSBLMTDP1BTN3A1MVD
SCHEMBL1577193 0.92 FDPS (0.50) FDPSBLMTDP1BTN3A1MVD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118369335-A N1-modified pseudouridine and application thereof in mRNA synthesis 上海吉量医药工程有限公司 2024-07-19 CN disclosed
WO-2023131254-A1 PSEUDOURIDINE MODIFIED AT N1 POSITION AND USE THEREOF IN MRNA SYNTHESIS 上海吉量医药工程有限公司 2023-07-13 WO disclosed
EP-1546399-B1 TERMINAL PHOSPHATE BLOCKED NUCLEOSIDE POLYPHOSPHATES GE HEALTHCARE BIO SCIENCES (US) 2012-02-29 EP disclosed
US-7452698-B2 Terminal phosphate blocked nucleoside polyphosphates GE HEALTHCARE BIO-SCIENCES CORP. (US) 2008-11-18 US disclosed
US-20070292879-A1 TERMINAL PHOSPHATE BLOCKED NUCLEOSIDE POLYPHOSPHATES GE HEALTHCARE BIO-SCIENCES CORP. (US) 2007-12-20 US disclosed
US-7256019-B2 Terminal phosphate blocked nucleoside polyphosphates GE HEALTHCARE BIO-SCIENCES CORP. (US) 2007-08-14 US disclosed
EP-1546399-A4 TERMINAL PHOSPHATE BLOCKED NUCLEOSIDE POLYPHOSPHATES GE HEALTHCARE BIO SCIENCES (US) 2007-07-25 EP disclosed
EP-1546399-A2 TERMINAL PHOSPHATE BLOCKED NUCLEOSIDE POLYPHOSPHATES Amersham Biosciences Corp. (US) 2005-06-29 EP disclosed
US-20040048300-A1 Terminal phosphate blocked nucleoside polyphosphates GLOBAL LIFE SCIENCES SOLUTIONS USA LLC 2004-03-11 US disclosed
WO-2004020602-A2 TERMINAL PHOSPHATE BLOCKED NUCLEOSIDE POLYPHOSPHATES AMERSHAM BIOSCIENCES CORP (US) 2004-03-11 WO disclosed