SCHEMBL412533

SCHEMBL412533

COP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.47
BLM P54132 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
BTN3A1 O00481 4/20 0.43
MVD P53602 3/20 0.33
FNTA P49354 3/20 0.32
PGGT1B P53609 2/20 0.32
FNTB P49356 1/20 0.32
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16855741 1.00 FDPS (0.47) FDPSBLMTDP1BTN3A1MVD
SCHEMBL687243 1.00 FDPS (0.47) FDPSBLMTDP1BTN3A1MVD
Ammonia Solution, Strong SCHEMBL28227868 0.97 FDPS (0.45) FDPSBLMTDP1BTN3A1MVD
SCHEMBL9580811 0.97 FDPS (0.45) FDPSBLMTDP1BTN3A1MVD
SCHEMBL10862597 0.97 FDPS (0.45) FDPSBLMTDP1BTN3A1MVD
Ammonia Solution, Strong SCHEMBL28227867 0.97 FDPS (0.45) FDPSBLMTDP1BTN3A1MVD
SCHEMBL19387807 0.94 FDPS (0.53) FDPSBLMTDP1BTN3A1MVD
SCHEMBL889928 0.94 FDPS (0.53) FDPSBLMTDP1BTN3A1MVD
Ammonia Solution, Strong SCHEMBL28569612 0.92 FDPS (0.50) FDPSBLMTDP1BTN3A1MVD
SCHEMBL1577193 0.92 FDPS (0.50) FDPSBLMTDP1BTN3A1MVD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736260-B Preparation method of nucleotide triphosphate 上海吉量医药工程有限公司 2024-08-23 CN claimed
CN-118165342-A Flame-retardant polyurethane heat-insulating core material and preparation method thereof 娄底潇湘职业学院 2024-06-11 CN claimed
CN-114656511-B Process for the preparation of acetylated cytosine triphosphates and intermediates therefor 上海吉量医药工程有限公司 2024-04-16 CN claimed
WO-2023185812-A1 METHOD FOR PREPARING ACETYLATED CYTOSINE TRIPHOSPHATE AND INTERMEDIATE THEREOF 上海吉量医药工程有限公司 2023-10-05 WO claimed
WO-2023185814-A1 METHOD FOR PREPARING NUCLEOTIDE TRIPHOSPHATE 上海吉量医药工程有限公司 2023-10-05 WO claimed
CN-114736260-A Preparation method of nucleotide triphosphate 上海吉量医药工程有限公司 2022-07-12 CN claimed
CN-114656511-A Preparation method of acetylated cytosine triphosphate and intermediate thereof 上海吉量医药工程有限公司 2022-06-24 CN claimed
EP-4714452-A1 METHODS FOR TREATING SARS COV-2 INFECTIONS Gilead Sciences, Inc. (US) 2026-03-25 EP disclosed
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-04-08 US disclosed
US-12247046-B2 Ribonucleic acids with 4′-thio-modified nucleotides and related methods TRANSLATE BIO, INC. (US) 2025-03-11 US disclosed
CN-119431334-A Preparation method of 2' OMe modified pseudouridine and N1 methyl pseudouridine 上海吉量医药工程有限公司 2025-02-14 CN disclosed
EP-4493573-A1 COMPOUNDS AND METHODS FOR TREATING DISEASE Rome Therapeutics, Inc. (US) 2025-01-22 EP disclosed
US-20240415923-A1 RNA-Dependent RNA Polymerase Inhibitory Compounds, Uses in Managing Viral Infections, and Pharmaceutical Compositions UNIV EMORY (US) 2024-12-19 US disclosed
US-20030138805-A1 Thermostable chimeric nucleic acid polymerases and uses thereof QIAGEN GMBH (DE) 2003-07-24 US disclosed
US-6503710-B2 Providing an amount of DNA containing the mutation, adding primers and a set of modified non-terminating nucleotide triphosphates (NTP) and terminating nucleotide triphosphates for the method of primer extension; hybridization; decomposing BRUKER DALTONIK GMBH (DE) 2003-01-07 US disclosed
EP-1259624-A2 THERMOSTABLE CHIMERIC NUCLEIC ACID POLYMERASES AND USES THEREOF QIAGEN GmbH (DE) 2002-11-27 EP disclosed
US-20020162622-A1 Providing an amount of DNA containing the mutation, adding primers and a set of modified non-terminating nucleotide triphosphates (NTP) and terminating nucleotide triphosphates for the method of primer extension; hybridization; decomposing BRUKER DALTONIK GMBH (DE) 2002-11-07 US disclosed
WO-2001061015-A2 THERMOSTABLE CHIMERIC NUCLEIC ACID POLYMERASES AND USES THEREOF QIAGEN GMBH (DE) 2001-08-23 WO disclosed
US-5354656-A Method of DNA sequencing STRATAGENE (US) 1994-10-11 US disclosed
WO-1991005065-A1 AN IMPROVED METHOD OF DNA SEQUENCING STRATAGENE (US) 1991-04-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12247046-B2 Ribonucleic acids with 4′-thio-modified nucleotides and related methods RNMT, RNGTT, NSUN3 FDPS 1030/4885BLM 2092/4885TDP1 402/4885
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ACE, ACE2, SPCS3 FDPS 1226/4885BLM 2901/4885TDP1 4684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.