Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 15/20 | 0.72 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553453 | 0.85 | GPR88 (0.66) | GPR88MEN1KMT2A | |
| SCHEMBL2499205 | 0.85 | GPR88 (0.66) | GPR88MEN1KMT2A | |
| SCHEMBL1554714 | 0.77 | GPR88 (0.55) | GPR88MEN1KMT2A | |
| SCHEMBL11904814 | 0.77 | GPR88 (0.55) | GPR88MEN1KMT2A | |
| SCHEMBL1554711 | 0.77 | GPR88 (0.55) | GPR88MEN1KMT2A | |
| SCHEMBL2499207 | 0.76 | GPR88 (1.00) | GPR88 | |
| SCHEMBL6871594 | 0.74 | GPR88 (0.54) | GPR88 | |
| SCHEMBL1554890 | 0.74 | GPR88 (0.74) | GPR88 | |
| SCHEMBL27887826 | 0.74 | GPR88 (0.74) | GPR88 | |
| SCHEMBL15127992 | 0.72 | GPR88 (0.52) | GPR88MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044195-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-04-14 | — | — | WO | disclosed |