Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554711 | 1.00 | GPR88 (0.55) | GPR88KMT2AL3MBTL1CARM1FFAR1 | |
| SCHEMBL1554714 | 1.00 | GPR88 (0.55) | GPR88KMT2AL3MBTL1CARM1FFAR1 | |
| SCHEMBL15127991 | 0.89 | GPR88 (0.48) | GPR88KMT2AL3MBTL1CARM1SMN1; SMN2 | |
| SCHEMBL15134951 | 0.87 | GPR88 (0.45) | GPR88KMT2AL3MBTL1CARM1SMN1; SMN2 | |
| SCHEMBL15121644 | 0.87 | GPR88 (0.47) | GPR88KMT2AL3MBTL1CARM1FFAR1 | |
| SCHEMBL15121578 | 0.78 | FFAR1 (0.54) | GPR88FFAR1 | |
| SCHEMBL6872905 | 0.77 | GPR88 (0.72) | GPR88KMT2AMEN1 | |
| SCHEMBL15121974 | 0.77 | GPR88 (0.47) | GPR88KMT2AL3MBTL1FFAR1 | |
| SCHEMBL11904853 | 0.73 | GPR88 (0.43) | GPR88L3MBTL1CARM1SMN1; SMN2FKBP1A | |
| SCHEMBL2499205 | 0.73 | GPR88 (0.66) | GPR88KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486030-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Bristol-Myers Squibb Company (US) | 2012-08-15 | — | — | EP | disclosed |