Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | MYB | P10242 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12901558 | 0.89 | GABBR2 (0.37) | GABBR2GABBR1GRM2 | |
| SCHEMBL2612420 | 0.87 | GABBR2 (0.41) | GABBR2GABBR1GAAALDH1A1HPGD | |
| SCHEMBL12901560 | 0.87 | GRM2 (0.39) | GABBR2GABBR1GRM2GAA | |
| SCHEMBL10135359 | 0.85 | GABBR2 (0.34) | GABBR2GABBR1 | |
| SCHEMBL1232621 | 0.85 | GAA (0.42) | GABBR2GABBR1GAAALDH1A1HPGD | |
| SCHEMBL29478047 | 0.84 | GABBR2 (0.41) | KIF11GABBR2GABBR1GAAALDH1A1 | |
| SCHEMBL493693 | 0.84 | GABBR2 (0.41) | KIF11GABBR2GABBR1GAAALDH1A1 | |
| SCHEMBL12901626 | 0.84 | GABBR2 (0.39) | GABBR2GABBR1GAAALDH1A1HPGD | |
| SCHEMBL30132965 | 0.84 | GABBR2 (0.41) | KIF11GABBR2GABBR1GAAALDH1A1 | |
| SCHEMBL6871678 | 0.84 | GABBR2 (0.41) | KIF11GABBR2GABBR1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464739-B1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2016-01-13 | — | — | EP | disclosed |
| US-8859235-B2 | Methods in cell cultures, and related inventions, employing certain additives | BASF SE (DE) | 2014-10-14 | — | — | US | disclosed |
| WO-2011018472-A2 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2011-02-17 | — | — | WO | disclosed |
| US-6809208-B2 | OXIDATION, HEAT AND LIGHT RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-10-26 | — | — | US | disclosed |
| US-20030212170-A1 | 3-Arylbenzofuranones with electron-withdrawing substituents as stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2003-11-13 | — | — | US | disclosed |
| EP-1263860-A1 | NEW 3-ARYLBENZOFURANONES WITH ELECTRON-WITHDRAWING SUBSTITUENTS AS STABILIZERS | Ciba SC Holding AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001059000-A1 | NEW 3-ARYLBENZOFURANONES WITH ELECTRON-WITHDRAWING SUBSTITUENTS AS STABILIZERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212170-A1 | 3-Arylbenzofuranones with electron-withdrawing substituents as stabilizers | CYP1B1, ALDH1A1, CYP1A1 | KIF11 2255/4885GABBR2 2286/4885GABBR1 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.