Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715142 | 0.90 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1FAAHMEN1 | |
| SCHEMBL6878782 | 0.86 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1FAAHMEN1 | |
| SCHEMBL11047003 | 0.67 | FAAH (0.44) | SLC1A3SLC1A2SLC1A1FAAHMEN1 | |
| SCHEMBL2108738 | 0.66 | CA1 (0.53) | FAAHMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2108741 | 0.66 | CA1 (0.53) | FAAHMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2619864 | 0.66 | CA1 (0.53) | FAAHMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17242670 | 0.64 | SLC1A1 (0.48) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL19656027 | 0.64 | SLC1A1 (0.48) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL17242673 | 0.64 | SLC1A1 (0.48) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL17241775 | 0.64 | SLC1A1 (0.48) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-B1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR INC (US) | 2004-01-14 | — | — | EP | disclosed |
| US-5763596-A | PYROLO PYRIMIDINE AND PYRAZOLO PYRIMIDINE COMPOUMDS; TREATMENT OF CARDIOVASCULAR AND BRAIN DISORDERS, ANTIINFLAMMATORY AGENTS | METABASIS THERAPEUTICS, INC. (US) | 1998-06-09 | — | — | US | disclosed |