Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 18/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 16/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 16/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868235 | 0.90 | ADORA2B (0.56) | ADORA2BADORA2AADORA1CHRM4 | |
| SCHEMBL6873671 | 0.87 | ADORA2B (0.50) | ADORA2BADORA2AADORA1CHRM4 | |
| SCHEMBL6875267 | 0.86 | DUSP3 (0.54) | ADORA2BADORA2AADORA1CHRM4 | |
| SCHEMBL6868703 | 0.86 | ADORA2B (0.57) | ADORA2BADORA2AADORA1CHRM4 | |
| SCHEMBL5713556 | 0.85 | ADORA2B (0.65) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6877728 | 0.84 | ADORA2B (0.72) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6868256 | 0.84 | ADORA2A (0.55) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6876108 | 0.83 | ADORA2B (0.79) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6872814 | 0.81 | ADORA2B (0.63) | ADORA2BADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL6876107 | 0.80 | ADORA2B (0.61) | ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456188-A1 | 7-AMINO-BENZOTHIAZOLE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| US-6713499-B2 | ADENOSINE RECEPTOR AGONIST | HOFFMAN-LA ROCHE INC. | 2004-03-30 | — | — | US | disclosed |
| US-20030153566-A1 | 7-Amino-benzothiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-14 | — | — | US | disclosed |
| WO-2003053946-A1 | 7-AMINO-BENZOTHIAZOLE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153566-A1 | 7-Amino-benzothiazole derivatives | ADORA1, ADORA2A, ADORA3 | ADORA2B 4/4885ADORA2A 2/4885ADORA1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.