Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873537 | 1.00 | KLKB1 (0.46) | KLKB1P2RX7NPSR1HDAC1HDAC2 | |
| SCHEMBL6875196 | 0.90 | CNR1 (0.53) | KLKB1NPSR1HDAC1HDAC2MCHR1 | |
| SCHEMBL6875191 | 0.90 | CNR1 (0.53) | KLKB1NPSR1HDAC1HDAC2MCHR1 | |
| SCHEMBL13793586 | 0.85 | MCHR1 (0.58) | P2RX7MCHR1ADRA2ANPY5R | |
| SCHEMBL6875795 | 0.83 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6878858 | 0.81 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6875316 | 0.81 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6878852 | 0.81 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6875313 | 0.81 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RACACBACACA | |
| SCHEMBL6456374 | 0.81 | ACACB (0.47) | MCHR1ADRA2ANPY5RACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |