Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875191 | 1.00 | CNR1 (0.53) | CNR1CNR2NPSR1KLKB1MCHR1 | |
| SCHEMBL6873542 | 0.90 | KLKB1 (0.46) | CNR1CNR2NPSR1KLKB1MCHR1 | |
| SCHEMBL6873537 | 0.90 | KLKB1 (0.46) | CNR1CNR2NPSR1KLKB1MCHR1 | |
| SCHEMBL13792947 | 0.84 | MCHR1 (0.65) | CNR1CNR2NPSR1MCHR1 | |
| SCHEMBL6867835 | 0.82 | PLK1 (0.50) | MCHR1RAB9A | |
| SCHEMBL6867842 | 0.82 | PLK1 (0.50) | MCHR1RAB9A | |
| SCHEMBL6875245 | 0.81 | MCHR1 (0.49) | MCHR1RAB9A | |
| SCHEMBL6875248 | 0.81 | MCHR1 (0.49) | MCHR1RAB9A | |
| SCHEMBL27651773 | 0.81 | MCHR1 (0.52) | MCHR1RAB9A | |
| SCHEMBL6875907 | 0.81 | MCHR1 (0.49) | MCHR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |