SCHEMBL687378

SCHEMBL687378

O=C(O)c1ccc(-c2ccccn2)nc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 5/20 0.74
P4HA1 P13674 3/20 0.74
LDHA P00338 1/20 0.68
KDM4E B2RXH2 4/20 0.64
KDM6B O15054 1/20 0.64
KDM4A O75164 1/20 0.64
KDM5C P41229 1/20 0.64
KDM4C Q9H3R0 1/20 0.64
KDM2A Q9Y2K7 1/20 0.64
KDM3A Q9Y4C1 1/20 0.64
HPGDS O60760 2/20 0.61
LMNA P02545 2/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
CCR1 P32246 1/20 0.52
CCR5 P51681 1/20 0.52
CCR8 P51685 1/20 0.52
METAP1 P53582 1/20 0.52
BLM P54132 1/20 0.52
HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29913684 1.00 P4HTM (0.74) P4HTMP4HA1LDHAKDM4EKDM6B
SCHEMBL29488117 0.98 P4HTM (0.71) P4HTMP4HA1LDHAKDM4EKDM6B
Hydrochloric Acid SCHEMBL29488111 0.98 P4HTM (0.71) P4HTMP4HA1LDHAKDM4EKDM6B
Dipyridyl SCHEMBL28600995 0.93 P4HTM (0.65) P4HTMP4HA1LDHAKDM4EKDM6B
SCHEMBL27001722 0.91 LDHA (0.62) P4HTMP4HA1LDHAKDM4EKDM6B
SCHEMBL12131264 0.86 P4HTM (0.58) P4HTMP4HA1LDHAKDM4EKDM6B
Dipyridyl SCHEMBL28117961 0.86 KDM4E (0.75) P4HTMP4HA1KDM4EKDM6BKDM4A
SCHEMBL29683317 0.86 P4HTM (1.00) P4HTMP4HA1LDHACYP1A2HCAR3
SCHEMBL68560 0.86 P4HTM (1.00) P4HTMP4HA1LDHACYP1A2HCAR3
SCHEMBL29397057 0.86 P4HTM (1.00) P4HTMP4HA1LDHACYP1A2HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114277026-B Magnetic bead for nucleic acid extraction, preparation method thereof and kit for nucleic acid extraction by magnetic bead method 深圳市易瑞生物技术股份有限公司 2023-07-14 CN claimed
CN-110903173-B Method for preparing L-menthone from R-citronellal 万华化学集团股份有限公司 2022-09-16 CN claimed
CN-114960191-A Super-hydrophobic photoluminescent cotton fabric, preparation method and application 南通大学 2022-08-30 CN claimed
CN-114345413-A Aromatic acid coordinated iron-cobalt nitrogen fixation catalyst and preparation method and application thereof 杭州师范大学 2022-04-15 CN claimed
CN-114277026-A Magnetic bead for nucleic acid extraction, preparation method thereof and kit for magnetic bead method nucleic acid extraction 深圳市易瑞生物技术股份有限公司 2022-04-05 CN claimed
CN-113603602-A Method for preparing beta-aminopropionic acid with high selectivity 万华化学集团股份有限公司 2021-11-05 CN claimed
EP-3844156-A1 TREATING LIVER DISORDERS Terns Pharmaceuticals, Inc. (US) 2021-07-07 EP claimed
CN-112892592-A A rhodium-based electron mediator [ Cp Rh (bpy) H2O]2+Method for fixing photocatalyst Uio-66-NH2 surface 中国科学院青岛生物能源与过程研究所 2021-06-04 CN claimed
CN-110903173-A Method for preparing L-menthone from R-citronellal 万华化学集团股份有限公司 2020-03-24 CN claimed
WO-2020042114-A1 TREATING LIVER DISORDERS TERNS PHARMACEUTICALS, INC. (KY) 2020-03-05 WO claimed
EP-1511882-A1 ACIDIC SOLUTION FOR SILVER DEPOSITION AND METHOD FOR SILVER LAYER DEPOSITION ON METAL SURFACES ATOTECH Deutschland GmbH (DE) 2005-03-09 EP claimed
EP-1490064-A1 SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE Pharmacia Corporation (US) 2004-12-29 EP claimed
WO-2003104527-A1 ACIDIC SOLUTION FOR SILVER DEPOSITION AND METHOD FOR SILVER LAYER DEPOSITION ON METAL SURFACES ATOTECH DEUTSCHLAND GMBH (DE) 2003-12-18 WO claimed
WO-2003068230-A1 SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE PHARMACIA CORPORATION (US) 2003-08-21 WO claimed
EP-1245697-A2 Process for electroles silver plating ATOTECH Deutschland GmbH (DE) 2002-10-02 EP claimed
EP-0552284-B1 ISOLATED METALLOPOLYPEPTIDE: COMPOSITIONS AND SYNTHETIC METHODS SCRIPPS RESEARCH INST (US) 2000-03-29 EP claimed
US-5408036-A A polyvalent ion covalently linked to 2 to 8 polypeptide binding ligands, each of which covalently bonded to a linear polypeptide THE SCRIPPS RESEARCH INSTITUTE (US) 1995-04-18 US claimed
EP-0552284-A4 1994-03-23 EP claimed
EP-0552284-A1 ISOLATED METALLOPOLYPEPTIDE: COMPOSITIONS AND SYNTHETIC METHODS THE SCRIPPS RESEARCH INSTITUTE (US) 1993-07-28 EP claimed
WO-1992006110-A1 ISOLATED METALLOPOLYPEPTIDE: COMPOSITIONS AND SYNTHETIC METHODS THE SCRIPPS RESEARCH INSTITUTE (US) 1992-04-16 WO claimed