Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 14/20 | 0.42 |
| ▸ | MMP1 | P03956 | 12/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770863 | 0.82 | MMP1 (0.60) | MMP13MMP1MMP12MMP2MMP3 | |
| SCHEMBL6770965 | 0.80 | PLG (0.52) | TSHRMMP13MMP1ALDH1A1USP2 | |
| SCHEMBL6954028 | 0.78 | MMP1 (0.69) | MMP13MMP1MMP12MMP2MMP3 | |
| SCHEMBL6771108 | 0.74 | MMP1 (0.51) | MMP13MMP1ALDH1A1USP2LMNA | |
| SCHEMBL6950277 | 0.74 | MMP1 (0.66) | MMP13MMP1MMP12MMP2MMP3 | |
| SCHEMBL6947434 | 0.72 | MMP1 (0.69) | MMP13MMP1MMP12MMP2MMP3 | |
| SCHEMBL6772598 | 0.72 | HTT (0.55) | TSHRMMP13ALDH1A1USP2LMNA | |
| SCHEMBL6954264 | 0.72 | MMP1 (0.70) | MMP13MMP1MMP12MMP2MMP3 | |
| Hydroxyamine SCHEMBL7578513 | 0.70 | HTT (0.53) | TSHRMMP13ALDH1A1USP2LMNA | |
| SCHEMBL7214305 | 0.69 | MMP1 (0.67) | MMP13MMP1MMP12MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210326-B1 | HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-02-25 | — | — | EP | claimed |