Sugi Predict

Sugi Predict / Compounds / Hydroxyamine

Hydroxyamine

Hydroxyamine

SCHEMBL7578513

NO.O=C(O)C1(NS(=O)(=O)c2ccc3c(c2)oc2ccccc23)CCCCC1.O=C(O)C1(NS(=O)(=O)c2ccc3c(c2)oc2ccccc23)CCCCC1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 3/20 0.53
▸ SMN1; SMN2 Q16637 3/20 0.53
▸ USP2 O75604 2/20 0.53
▸ PLG P00747 4/20 0.50
▸ PLAU P00749 4/20 0.50
▸ PLAT P00750 1/20 0.48
▸ MMP12 P39900 4/20 0.43
▸ MMP13 P45452 4/20 0.43
▸ LMNA P02545 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ TSHR P16473 1/20 0.42
▸ PTGDR Q13258 1/20 0.41
▸ NPC1 O15118 2/20 0.40
▸ RAB9A P51151 2/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ GAA P10253 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ TP53 P04637 2/20 0.40
▸ CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6772598 0.98 HTT (0.55) HTTSMN1; SMN2USP2PLGPLAU
SCHEMBL7065810 0.91 SMN1; SMN2 (0.55) HTTSMN1; SMN2USP2PLGPLAU
SCHEMBL6770965 0.88 PLG (0.52) HTTSMN1; SMN2USP2PLGPLAU
SCHEMBL6771108 0.87 MMP1 (0.51) HTTSMN1; SMN2USP2MMP13LMNA
SCHEMBL7454421 0.86 PLAU (0.46) HTTSMN1; SMN2USP2PLGPLAU
SCHEMBL6417494 0.85 MMP12 (0.56) HTTSMN1; SMN2USP2MMP12MMP13
SCHEMBL23673553 0.85 USP2 (0.51) HTTSMN1; SMN2USP2PLGPLAU
Hydroxyamine SCHEMBL7552923 0.83 SMN1; SMN2 (0.52) HTTSMN1; SMN2USP2PLGPLAU
SCHEMBL23693947 0.83 USP2 (0.51) HTTSMN1; SMN2USP2PLGPLAU
SCHEMBL6772621 0.81 USP2 (0.49) HTTSMN1; SMN2USP2PLGPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210326-A2 HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY (US) 2002-06-05 — — EP disclosed
WO-2001012592-A2 HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY (US) 2001-02-22 — — WO disclosed
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