Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528437 | 0.93 | CTSL (0.48) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL6590412 | 0.93 | SMYD3 (0.46) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL5528527 | 0.89 | CTSL (0.48) | CTSLCTSBCTSSCTSKPKM | |
| SCHEMBL5526266 | 0.89 | CTSL (0.53) | CTSLCTSBCTSSCTSKATM | |
| SCHEMBL5525358 | 0.88 | PRMT5 (0.51) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL5534377 | 0.88 | CTSL (0.49) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL7562354 | 0.87 | CTSL (0.48) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL5529205 | 0.86 | PYGL (0.55) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL5525342 | 0.86 | CTSL (0.60) | CTSLCTSBCTSSCTSKSMN1; SMN2 | |
| SCHEMBL5520691 | 0.86 | CTSL (0.50) | CTSLCTSBCTSSCTSKPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |