Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874492 | 1.00 | EPHX1 (0.54) | EPHX1EPHX2CXCR3MCHR1ADRA2A | |
| SCHEMBL6868351 | 0.92 | USP30 (0.46) | EPHX1MCHR1ADRA2ANPC1RAB9A | |
| SCHEMBL6868346 | 0.92 | USP30 (0.46) | EPHX1MCHR1ADRA2ANPC1RAB9A | |
| SCHEMBL6874499 | 0.90 | MCHR1 (0.44) | EPHX1EPHX2MCHR1ADRA2ASMN1; SMN2 | |
| SCHEMBL6874504 | 0.90 | MCHR1 (0.44) | EPHX1EPHX2MCHR1ADRA2ASMN1; SMN2 | |
| SCHEMBL6874878 | 0.90 | NPC1 (0.54) | EPHX1EPHX2MCHR1ADRA2ASMN1; SMN2 | |
| SCHEMBL6874872 | 0.90 | NPC1 (0.54) | EPHX1EPHX2MCHR1ADRA2ASMN1; SMN2 | |
| SCHEMBL6876262 | 0.89 | SMN1; SMN2 (0.55) | EPHX1MCHR1ADRA2ASMN1; SMN2TP53 | |
| SCHEMBL6877480 | 0.89 | NOX1 (0.48) | EPHX1EPHX2MCHR1ADRA2ASMN1; SMN2 | |
| SCHEMBL6877475 | 0.89 | NOX1 (0.48) | EPHX1EPHX2MCHR1ADRA2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |