Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.50 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875251 | 1.00 | MCHR1 (0.50) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6880381 | 0.90 | MCHR1 (0.51) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6880005 | 0.90 | RAB9A (0.55) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6879998 | 0.90 | RAB9A (0.55) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6875039 | 0.90 | EPHX1 (0.51) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6875033 | 0.90 | EPHX1 (0.51) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6879414 | 0.90 | MCHR1 (0.46) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6879419 | 0.90 | MCHR1 (0.46) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6873166 | 0.87 | MCHR1 (0.50) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6873172 | 0.87 | MCHR1 (0.50) | MCHR1ADRA2AHRH1HTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |