Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875664 | 1.00 | RAB9A (0.49) | RAB9ANPC1KMT2AHTR1ADRD2 | |
| SCHEMBL6457802 | 0.86 | MCHR1 (0.47) | RAB9ANPC1KMT2AHTR1AKDM4E | |
| SCHEMBL6463577 | 0.86 | MCHR1 (0.47) | RAB9ANPC1KMT2AHTR1AKDM4E | |
| SCHEMBL6460413 | 0.85 | MCHR1 (0.48) | RAB9ANPC1KMT2AHTR1AKDM4E | |
| SCHEMBL6467599 | 0.85 | MCHR1 (0.48) | RAB9ANPC1KMT2AHTR1AKDM4E | |
| SCHEMBL6458843 | 0.85 | HPGD (0.48) | RAB9ANPC1KMT2AHTR1AKDM4E | |
| SCHEMBL6458853 | 0.85 | HPGD (0.48) | RAB9ANPC1KMT2AHTR1AKDM4E | |
| SCHEMBL6877277 | 0.85 | MCHR1 (0.48) | RAB9ANPC1KMT2AHTR1AHPGD | |
| SCHEMBL6877271 | 0.85 | MCHR1 (0.48) | RAB9ANPC1KMT2AHTR1AHPGD | |
| SCHEMBL6879865 | 0.84 | MCHR1 (0.57) | RAB9AHTR1AKDM4ESMN1; SMN2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |