Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280491 | 0.87 | TDP1 (0.56) | KMT2ATDP1SLC6A2SLC6A3PPARG | |
| SCHEMBL4650584 | 0.79 | KMT2A (0.76) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL28984037 | 0.78 | TDP1 (0.69) | KMT2ATDP1SLC6A2SLC6A3PPARG | |
| SCHEMBL6154855 | 0.76 | TDP1 (0.53) | KMT2ATDP1SLC6A2SLC6A3PPARG | |
| SCHEMBL6245188 | 0.76 | PPARG (0.61) | KMT2ATDP1SLC6A2SLC6A3PPARG | |
| SCHEMBL16758178 | 0.75 | TDP1 (0.69) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL6564486 | 0.75 | TDP1 (0.54) | KMT2ATDP1SLC6A2SLC6A3PPARG | |
| SCHEMBL6511919 | 0.74 | KMT2A (0.73) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL6472102 | 0.74 | TDP1 (0.57) | KMT2ATDP1SLC6A2SLC6A3PPARG | |
| SCHEMBL5085480 | 0.73 | PPARG (0.71) | KMT2ATDP1SLC6A2SLC6A3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395538-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094754-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2002-11-28 | — | — | WO | disclosed |