SCHEMBL5085480

SCHEMBL5085480

O=C(OCc1ccccc1COC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.71
TDP1 Q9NUW8 3/20 0.70
KMT2A Q03164 3/20 0.70
SLC6A2 P23975 1/20 0.70
SLC6A3 Q01959 1/20 0.70
MAPK1 P28482 2/20 0.59
HIF1A Q16665 1/20 0.59
LMNA P02545 4/20 0.58
ALDH1A1 P00352 3/20 0.57
NPSR1 Q6W5P4 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.54
F2 P00734 1/20 0.54
TSHR P16473 2/20 0.53
MAPT P10636 3/20 0.50
RAB9A P51151 2/20 0.50
HPGD P15428 1/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
POLB P06746 1/20 0.50
PKM P14618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6243415 0.92 PPARG (0.63) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL6245188 0.91 PPARG (0.61) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL28982407 0.91 PPARG (0.61) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL3674585 0.91 PPARG (0.61) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL4577944 0.90 PPARG (0.65) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL27841681 0.90 PPARG (0.60) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL336833 0.88 PPARG (0.63) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL4070163 0.88 LMNA (0.70) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL471706 0.87 PPARG (0.61) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL5421974 0.87 L3MBTL1 (0.72) PPARGTDP1KMT2ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3050906-B1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORP LTD (IN) 2020-07-22 EP disclosed
US-9873752-B2 Catalyst process modification and polymerization thereof INDIAN OIL CORPORATION LTD. (IN) 2018-01-23 US disclosed
US-9873752-B2 Catalyst process modification and polymerization thereof INDIAN OIL CORPORATION LTD. (IN) 2018-01-23 US disclosed
EP-3050906-A1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF Indian Oil Corporation Limited (IN) 2016-08-03 EP disclosed
US-20160215077-A1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORPORATION LTD. (IN) 2016-07-28 US disclosed
US-20160215077-A1 CATALYST PROCESS MODIFICATION AND POLYMERIZATION THEREOF INDIAN OIL CORPORATION LTD. (IN) 2016-07-28 US disclosed
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed
US-4283565-A REACTING A BENZYL HALIDE WITH A FORMATE, CONTACTING WITH AN ALCOHOL TO TRANSESTERIFY DYNAMIT NOBEL AG (DE) 1981-08-11 US disclosed