Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688233 | 0.93 | PTGER3 (0.43) | PTGER3MAPTP2RX7CNR2PDE7A | |
| SCHEMBL688343 | 0.91 | PTGER3 (0.43) | PTGER3MAPTP2RX7CNR2PDE7A | |
| SCHEMBL688053 | 0.89 | PTGER3 (0.43) | PTGER3MAPTCNR2SLC22A12TP53 | |
| SCHEMBL686799 | 0.89 | PTGER3 (0.51) | PTGER3MAPTCNR2SLC22A12THRB | |
| SCHEMBL686842 | 0.89 | PTGER3 (0.45) | PTGER3MAPTCNR2SLC22A12TP53 | |
| SCHEMBL687333 | 0.88 | PTGER3 (0.47) | PTGER3MAPTPDE7ATP53LMNA | |
| SCHEMBL687527 | 0.88 | ITGB1 (0.42) | PTGER3MAPTP2RX7CNR2TP53 | |
| SCHEMBL688669 | 0.88 | PTGER3 (0.42) | PTGER3MAPTCNR2CTSA | |
| SCHEMBL688215 | 0.87 | PTGER3 (0.43) | PTGER3MAPTP2RX7CTSA | |
| SCHEMBL688442 | 0.87 | PTGER3 (0.42) | PTGER3MAPTCNR2SLC22A12TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |