Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689679 | 0.84 | PTAFR (0.32) | NR1H4PTAFRGRIA2GRIA4BRD4 | |
| SCHEMBL5689802 | 0.84 | TSHR (0.35) | NR1H4PTAFRGRIA2GRIA4BRD4 | |
| SCHEMBL7106420 | 0.81 | NPC1 (0.38) | NR1H4PTAFRGRIA2GRIA4NPC1 | |
| SCHEMBL6231375 | 0.77 | BRD4 (0.32) | PTAFRBRD4CREBBP | |
| SCHEMBL5688730 | 0.77 | PTAFR (0.31) | PTAFRBRD4CREBBPTSHRNPC1 | |
| SCHEMBL5691597 | 0.76 | TSHR (0.35) | PTAFRBRD4CREBBPTSHRNPC1 | |
| SCHEMBL7111654 | 0.74 | NPC1 (0.36) | PTAFRNPC1RAB9ALMNAMAPT | |
| SCHEMBL28755373 | 0.73 | — | — | |
| SCHEMBL5689619 | 0.72 | HEXA (0.38) | RAB9ASMN1; SMN2KIF11 | |
| SCHEMBL5689474 | 0.72 | RXRA (0.33) | PTAFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397371-A1 | METALLOCENES AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | Basell Polyolefine GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003000706-A1 | METALLOCENES, USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2003-01-03 | — | — | WO | disclosed |