Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232636 | 0.89 | BRD4 (0.30) | BRD4CREBBP | |
| SCHEMBL5689802 | 0.78 | TSHR (0.35) | BRD4CREBBPPTAFR | |
| SCHEMBL5689679 | 0.78 | PTAFR (0.32) | BRD4CREBBPPTAFR | |
| SCHEMBL6876306 | 0.77 | NR1H4 (0.32) | BRD4CREBBPPTAFR | |
| SCHEMBL7106420 | 0.75 | NPC1 (0.38) | PTAFR | |
| SCHEMBL15668689 | 0.74 | PTAFR (0.34) | BRD4CREBBPCHRM3PTAFR | |
| SCHEMBL6232128 | 0.72 | PTAFR (0.33) | CHRM3PTAFR | |
| SCHEMBL5688730 | 0.71 | PTAFR (0.31) | BRD4CREBBPPTAFR | |
| SCHEMBL5691597 | 0.70 | TSHR (0.35) | BRD4CREBBPPTAFR | |
| SCHEMBL253624 | 0.69 | BRD4 (0.33) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313747-B1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |