Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69583 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP3A4TP53TDP1 | |
| SCHEMBL15485452 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TP53TDP1GAA | |
| SCHEMBL204468 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TP53TDP1GAA | |
| SCHEMBL11085769 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4TP53TDP1 | |
| SCHEMBL5848639 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4TP53TDP1 | |
| SCHEMBL28040473 | 0.77 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TP53TDP1GAA | |
| SCHEMBL27408439 | 0.75 | CYP3A4 (0.43) | ALDH1A1CYP3A4TDP1GAAMAPT | |
| SCHEMBL2131880 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4TP53TDP1 | |
| SCHEMBL394882 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4TP53TDP1 | |
| SCHEMBL29738345 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127363-A1 | TYK2 PSEUDOKINASE LIGANDS AND USES THEREOF | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2024-06-20 | — | — | WO | disclosed |
| US-9957241-B2 | Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor | SEIKA CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | SEIKA CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| CN-107531652-A | Aromatic diamine, intermediate thereof, and processes for producing these | 精化株式会社 | 2018-01-02 | — | — | CN | disclosed |
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-07 | — | — | US | disclosed |
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-07 | — | — | US | disclosed |
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-07 | — | — | US | disclosed |
| WO-2014087431-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-06-12 | — | — | WO | disclosed |
| WO-2014087431-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-06-12 | — | — | WO | disclosed |
| EP-1637122-B1 | 2-(Amino or substituted Amino)-3-5-6-substituted Phenol compounds, dyeing compositions containing them, and use thereof | PROCTER & GAMBLE (US) | 2012-02-29 | — | — | EP | disclosed |
| US-7338537-B2 | 2-(amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338537-B2 | 2-(amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338537-B2 | 2-(amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| CN-101005820-A | 2-(amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | PROCTER & GAMBLE (US) | 2007-07-25 | — | — | CN | disclosed |
| EP-1637122-A1 | 2-(Amino or substituted Amino)-3-5-6-substituted Phenol compounds, dyeing compositions containing them, and use thereof | The Procter & Gamble Company (US) | 2006-03-22 | — | — | EP | disclosed |
| WO-2006023438-A1 | 2-(AMINO OR SUBSTITUTED AMINO)-3-5-6-SUBSTITUTED PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060032000-A1 | 2-(Amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194279-A1 | ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS | TRRAP, NAT1, AHR | ALDH1A1 445/4885TSHR 39/4885CYP3A4 167/4885 |
| US-20060032000-A1 | 2-(Amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | KRT18, S100A6, S100A4 | ALDH1A1 459/4885TSHR 4867/4885CYP3A4 1922/4885 |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | WEE1, WEE2, WASF2 | ALDH1A1 544/4885TSHR 4030/4885CYP3A4 933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.