Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456993 | 1.00 | MCHR1 (0.41) | MCHR1ACHEADRA2ANPY5RBACE1 | |
| SCHEMBL6875802 | 0.87 | ACHE (0.48) | MCHR1ACHEBACE1 | |
| SCHEMBL6875798 | 0.87 | ACHE (0.48) | MCHR1ACHEBACE1 | |
| SCHEMBL6877562 | 0.84 | ACHE (0.39) | MCHR1ACHEADRA2ANPY5RBACE1 | |
| SCHEMBL6465890 | 0.84 | ACHE (0.39) | MCHR1ACHEADRA2ANPY5RBACE1 | |
| SCHEMBL6878788 | 0.83 | MCHR1 (0.39) | MCHR1ACHEADRA2ANPY5RBACE1 | |
| SCHEMBL6876987 | 0.83 | ACHE (0.46) | MCHR1ACHEADRA2ANPY5RBACE1 | |
| SCHEMBL6878784 | 0.83 | MCHR1 (0.39) | MCHR1ACHEADRA2ANPY5RBACE1 | |
| SCHEMBL6876992 | 0.83 | ACHE (0.46) | MCHR1ACHEADRA2ANPY5RBACE1 | |
| SCHEMBL6868802 | 0.83 | ACHE (0.46) | MCHR1ACHEADRA2ANPY5RBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |