Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266574 | 0.91 | ALDH1A1 (0.48) | ALDH1A1PLAUCYP1A2F2PRSS1 | |
| SCHEMBL7798549 | 0.86 | ALDH1A1 (0.41) | ALDH1A1PLAUCYP1A2F2PRSS1 | |
| SCHEMBL6876467 | 0.83 | LMNA (0.53) | ALDH1A1PLAUCYP1A2F2PRSS1 | |
| SCHEMBL8507058 | 0.82 | LMNA (0.59) | ALDH1A1CYP1A2CYP3A4BLMPMP22 | |
| SCHEMBL31215053 | 0.82 | TPMT (0.45) | ALDH1A1PLAUCYP1A2F2PRSS1 | |
| SCHEMBL1626717 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HDAC6LMNAMAPTMEN1 | |
| SCHEMBL828586 | 0.81 | ALDH1A1 (0.64) | ALDH1A1CYP1A2F2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL27319280 | 0.79 | ALDH1A1 (0.62) | ALDH1A1CYP1A2F2PRSS1PRSS2 | |
| SCHEMBL1566720 | 0.79 | ALDH1A1 (0.62) | ALDH1A1CYP1A2F2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL6274668 | 0.79 | ALDH1A1 (0.62) | ALDH1A1CYP1A2F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-B1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR INC (US) | 2004-01-14 | — | — | EP | disclosed |