Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876645 | 1.00 | MCHR1 (0.43) | MCHR1RXFP1KMT2ANPY5RADRA2A | |
| SCHEMBL6872317 | 0.89 | KMT2A (0.51) | MCHR1RXFP1KMT2AKDM4ELMNA | |
| SCHEMBL6872319 | 0.89 | KMT2A (0.51) | MCHR1RXFP1KMT2AKDM4ELMNA | |
| SCHEMBL6878604 | 0.86 | MCHR1 (0.48) | MCHR1KMT2ANPY5RADRA2ASMN1; SMN2 | |
| SCHEMBL6878610 | 0.86 | MCHR1 (0.48) | MCHR1KMT2ANPY5RADRA2ASMN1; SMN2 | |
| SCHEMBL6879386 | 0.86 | MCHR1 (0.47) | MCHR1NPY5RADRA2ASMN1; SMN2KDM4E | |
| SCHEMBL6879382 | 0.86 | MCHR1 (0.47) | MCHR1NPY5RADRA2ASMN1; SMN2KDM4E | |
| SCHEMBL6876360 | 0.85 | MCHR1 (0.47) | MCHR1KMT2ANPY5RADRA2ASMN1; SMN2 | |
| SCHEMBL6876357 | 0.85 | MCHR1 (0.47) | MCHR1KMT2ANPY5RADRA2ASMN1; SMN2 | |
| SCHEMBL6878289 | 0.84 | KDM4E (0.48) | MCHR1NPY5RADRA2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |