Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 11/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876973 | 1.00 | MEN1 (0.37) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL6876968 | 1.00 | MEN1 (0.37) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL27594296 | 0.84 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL6852736 | 0.82 | KMT2A (0.38) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL6875888 | 0.82 | KMT2A (0.38) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL6852733 | 0.82 | KMT2A (0.38) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL6276439 | 0.82 | ADRB2 (0.42) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL6879073 | 0.82 | ADRB2 (0.42) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL6309957 | 0.82 | ADRB2 (0.42) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL6850708 | 0.75 | MEN1 (0.38) | MEN1KMT2ANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |