Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875888 | 1.00 | KMT2A (0.38) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL6852733 | 1.00 | KMT2A (0.38) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL6876968 | 0.82 | MEN1 (0.37) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL6876973 | 0.82 | MEN1 (0.37) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL6876971 | 0.82 | MEN1 (0.37) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL6879073 | 0.78 | ADRB2 (0.42) | KMT2AMEN1NPC1CLK4CYP2A6 | |
| SCHEMBL6276439 | 0.78 | ADRB2 (0.42) | KMT2AMEN1NPC1CLK4CYP2A6 | |
| SCHEMBL6309957 | 0.78 | ADRB2 (0.42) | KMT2AMEN1NPC1CLK4CYP2A6 | |
| SCHEMBL6870896 | 0.76 | ALDH1A1 (0.43) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL6854162 | 0.74 | LMNA (0.39) | KMT2AMEN1NPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |