Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877318 | 1.00 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RKDM1AMAOA | |
| SCHEMBL6868214 | 0.92 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RKMT2AMEN1 | |
| SCHEMBL6455511 | 0.92 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RKMT2AMEN1 | |
| SCHEMBL6877157 | 0.89 | MCHR1 (0.51) | MCHR1ADRA2AKDM1AMAOAKMT2A | |
| SCHEMBL6877152 | 0.89 | MCHR1 (0.51) | MCHR1ADRA2AKDM1AMAOAKMT2A | |
| SCHEMBL6877347 | 0.89 | MCHR1 (0.45) | MCHR1ADRA2ANPY5RKMT2APOLB | |
| SCHEMBL6877351 | 0.89 | MCHR1 (0.45) | MCHR1ADRA2ANPY5RKMT2APOLB | |
| SCHEMBL6874814 | 0.87 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RKDM1AMAOA | |
| SCHEMBL6873706 | 0.87 | ACHE (0.54) | MCHR1ADRA2ANPY5RKMT2AMEN1 | |
| SCHEMBL6462424 | 0.87 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |