Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877170 | 1.00 | MCHR1 (0.38) | MCHR1ADRA2ASMN1; SMN2LMNAHPGD | |
| SCHEMBL6873185 | 0.84 | MCHR1 (0.43) | MCHR1ADRA2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL6873180 | 0.84 | MCHR1 (0.43) | MCHR1ADRA2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL6873170 | 0.84 | MCHR1 (0.43) | MCHR1ADRA2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL6878524 | 0.81 | MCHR1 (0.42) | MCHR1ADRA2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6878517 | 0.81 | MCHR1 (0.42) | MCHR1ADRA2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6462958 | 0.80 | MCHR1 (0.42) | MCHR1ADRA2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL6462961 | 0.80 | MCHR1 (0.42) | MCHR1ADRA2ASMN1; SMN2LMNARAB9A | |
| SCHEMBL6874734 | 0.79 | LMNA (0.36) | MCHR1SMN1; SMN2LMNAHPGDRAB9A | |
| SCHEMBL6874724 | 0.79 | LMNA (0.36) | MCHR1SMN1; SMN2LMNAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |