Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873180 | 1.00 | MCHR1 (0.43) | MCHR1ADRA2APOLBMAPTCYP1A2 | |
| SCHEMBL6873185 | 1.00 | MCHR1 (0.43) | MCHR1ADRA2APOLBMAPTCYP1A2 | |
| SCHEMBL6872664 | 0.84 | MCHR1 (0.43) | MCHR1ADRA2APOLBMAPTMEN1 | |
| SCHEMBL6872666 | 0.84 | MCHR1 (0.43) | MCHR1ADRA2APOLBMAPTMEN1 | |
| SCHEMBL6877165 | 0.84 | MCHR1 (0.38) | MCHR1ADRA2AMAPTNPY5RLMNA | |
| SCHEMBL6877170 | 0.84 | MCHR1 (0.38) | MCHR1ADRA2AMAPTNPY5RLMNA | |
| SCHEMBL6881234 | 0.83 | MCHR1 (0.46) | MCHR1ADRA2APOLBMEN1KMT2A | |
| SCHEMBL6881237 | 0.83 | MCHR1 (0.46) | MCHR1ADRA2APOLBMEN1KMT2A | |
| SCHEMBL6880541 | 0.82 | MCHR1 (0.41) | MCHR1ADRA2AMAPTMEN1KMT2A | |
| SCHEMBL6878517 | 0.82 | MCHR1 (0.42) | MCHR1ADRA2ACYP1A2CYP3A4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |