Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457420 | 1.00 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RHTR2AHTR2C | |
| SCHEMBL6875398 | 0.89 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RALDH1A1MEN1 | |
| SCHEMBL6462999 | 0.89 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RALDH1A1MEN1 | |
| SCHEMBL6878836 | 0.85 | MCHR1 (0.57) | MCHR1ADRA2ANPY5RDRD2DRD3 | |
| SCHEMBL6878830 | 0.85 | MCHR1 (0.57) | MCHR1ADRA2ANPY5RDRD2DRD3 | |
| SCHEMBL6875956 | 0.85 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RHTR2BMEN1 | |
| SCHEMBL6875950 | 0.85 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RHTR2BMEN1 | |
| SCHEMBL6874708 | 0.83 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RHTR2BMEN1 | |
| SCHEMBL6873498 | 0.83 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RHTR2BMEN1 | |
| SCHEMBL6874714 | 0.83 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RHTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |