Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462999 | 1.00 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RALDH1A1SLC2A1 | |
| SCHEMBL6457420 | 0.89 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RALDH1A1DRD2 | |
| SCHEMBL6877348 | 0.89 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RALDH1A1DRD2 | |
| SCHEMBL6457227 | 0.89 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RMAPK14DRD2 | |
| SCHEMBL6876367 | 0.89 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RMAPK14DRD2 | |
| SCHEMBL6876624 | 0.89 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RHCRTR2MAPK14 | |
| SCHEMBL6876619 | 0.89 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RHCRTR2MAPK14 | |
| SCHEMBL6874708 | 0.88 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RCDK4MAPK14 | |
| SCHEMBL6874714 | 0.88 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RCDK4MAPK14 | |
| SCHEMBL6878043 | 0.88 | SLC2A1 (0.43) | MCHR1ADRA2AALDH1A1SLC2A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |