Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077672 | 0.89 | L3MBTL1 (0.43) | PLA2G7L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL14262702 | 0.81 | PLA2G7 (0.45) | PLA2G7L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6077681 | 0.77 | CYP1A2 (0.49) | PLA2G7L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6077675 | 0.77 | CYP1A2 (0.49) | PLA2G7L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL14262727 | 0.74 | PLA2G7 (0.45) | PLA2G7L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL4719950 | 0.74 | PLA2G7 (0.47) | PLA2G7SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6077150 | 0.73 | PPARG (0.45) | PLA2G7L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6077147 | 0.73 | PPARG (0.45) | PLA2G7L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL670003 | 0.71 | PLA2G7 (0.54) | PLA2G7L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL670004 | 0.71 | PLA2G7 (0.54) | PLA2G7L3MBTL1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777440-B2 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-17 | — | — | US | disclosed |
| US-20030176495-A1 | HIV Integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176495-A1 | HIV Integrase inhibitors | MAPT, RIF1, HPRT1 | PLA2G7 4373/4885L3MBTL1 480/4885LMNA 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.