Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877575 | 1.00 | ALPL (0.50) | ALPLALPIALPGNPC1KMT2A | |
| SCHEMBL6877344 | 1.00 | ALPL (0.50) | ALPLALPIALPGNPC1KMT2A | |
| SCHEMBL6877350 | 1.00 | ALPL (0.50) | ALPLALPIALPGNPC1KMT2A | |
| SCHEMBL6876759 | 0.91 | MCHR1 (0.40) | ALPLALPIALPGNPC1MCHR1 | |
| SCHEMBL6876764 | 0.91 | MCHR1 (0.40) | ALPLALPIALPGNPC1MCHR1 | |
| SCHEMBL6868670 | 0.91 | MCHR1 (0.44) | ALPLALPIALPGKMT2AMCHR1 | |
| SCHEMBL6868666 | 0.91 | MCHR1 (0.44) | ALPLALPIALPGKMT2AMCHR1 | |
| SCHEMBL6875593 | 0.89 | EPHX1 (0.54) | MCHR1ADRA2AEPHX1LMNAHTR1A | |
| SCHEMBL6875584 | 0.89 | EPHX1 (0.54) | MCHR1ADRA2AEPHX1LMNAHTR1A | |
| SCHEMBL6456857 | 0.86 | MCHR1 (0.39) | NPC1KMT2AMCHR1ADRA2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |