Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456848 | 1.00 | BCHE (0.43) | BCHEACHEADRA2ANPY5RMCHR1 | |
| SCHEMBL6458578 | 0.90 | BCHE (0.44) | BCHEACHELMNAHTR2AKDM4E | |
| SCHEMBL6874191 | 0.90 | BCHE (0.44) | BCHEACHELMNAHTR2AKDM4E | |
| SCHEMBL6460992 | 0.89 | MCHR1 (0.49) | BCHEACHEADRA2ANPY5RMCHR1 | |
| SCHEMBL6878992 | 0.89 | MCHR1 (0.49) | BCHEACHEADRA2ANPY5RMCHR1 | |
| SCHEMBL6457143 | 0.87 | NPY5R (0.46) | BCHEACHEADRA2ANPY5RMCHR1 | |
| SCHEMBL6876052 | 0.87 | NPY5R (0.46) | BCHEACHEADRA2ANPY5RMCHR1 | |
| SCHEMBL6867249 | 0.85 | MCHR1 (0.48) | ADRA2ANPY5RMCHR1LMNAMAPT | |
| SCHEMBL6457972 | 0.85 | MCHR1 (0.44) | ADRA2ANPY5RMCHR1KDM4EMAPT | |
| SCHEMBL6873945 | 0.85 | MCHR1 (0.44) | ADRA2ANPY5RMCHR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |