Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460992 | 1.00 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RBCHEACHE | |
| SCHEMBL6457965 | 0.90 | ADRA2A (0.46) | MCHR1ADRA2ANPY5RBCHEACHE | |
| SCHEMBL6874250 | 0.90 | ADRA2A (0.46) | MCHR1ADRA2ANPY5RBCHEACHE | |
| SCHEMBL6456848 | 0.89 | BCHE (0.43) | MCHR1ADRA2ANPY5RBCHEACHE | |
| SCHEMBL6878474 | 0.89 | BCHE (0.43) | MCHR1ADRA2ANPY5RBCHEACHE | |
| SCHEMBL6876052 | 0.88 | NPY5R (0.46) | MCHR1ADRA2ANPY5RBCHEACHE | |
| SCHEMBL6457143 | 0.88 | NPY5R (0.46) | MCHR1ADRA2ANPY5RBCHEACHE | |
| SCHEMBL13796380 | 0.85 | MCHR1 (0.68) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL6875028 | 0.83 | MCHR1 (0.53) | MCHR1ADRA2ANPY5RADRA1AHRH1 | |
| SCHEMBL6875024 | 0.83 | MCHR1 (0.53) | MCHR1ADRA2ANPY5RADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |