Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878555 | 1.00 | MCHR1 (0.42) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6880610 | 0.89 | CCNC (0.47) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6880615 | 0.89 | CCNC (0.47) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6877944 | 0.88 | NPC1 (0.55) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6877951 | 0.88 | NPC1 (0.55) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6876054 | 0.87 | MCHR1 (0.46) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6876048 | 0.87 | MCHR1 (0.46) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6458072 | 0.83 | MCHR1 (0.47) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6458078 | 0.83 | MCHR1 (0.47) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6876068 | 0.81 | ALDH1A1 (0.48) | MCHR1ADRA2AHRH1HTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |