Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878695 | 0.84 | NAAA (0.40) | NAAAFFAR4ACERENL3MBTL1 | |
| SCHEMBL7043476 | 0.80 | NAAA (0.45) | NAAAL3MBTL1EPHX1CYP19A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6880169 | 0.79 | NAAA (0.44) | NAAAL3MBTL1EPHX1CYP19A1ALDH1A1 | |
| SCHEMBL231985 | 0.75 | NAAA (0.45) | NAAAL3MBTL1EPHX1CYP19A1SMN1; SMN2 | |
| SCHEMBL18098083 | 0.71 | CYP19A1 (0.42) | NAAAL3MBTL1EPHX1CYP19A1SMN1; SMN2 | |
| SCHEMBL7218260 | 0.71 | NAAA (0.55) | NAAAL3MBTL1EPHX1CYP19A1ALDH1A1 | |
| SCHEMBL18098075 | 0.71 | CYP19A1 (0.42) | NAAAL3MBTL1EPHX1CYP19A1SMN1; SMN2 | |
| SCHEMBL7222848 | 0.70 | NAAA (0.58) | NAAAEPHX1CYP19A1ALDH1A1 | |
| SCHEMBL6295117 | 0.70 | FFAR4 (0.48) | FFAR4FFAR1ALDH1A1LMNAENPEP | |
| SCHEMBL17910035 | 0.69 | NAAA (0.43) | NAAAL3MBTL1EPHX1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463713-A1 | PRODRUGS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003045898-A1 | PRODRUGS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-06-05 | — | — | WO | disclosed |