Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6880169 | 0.99 | NAAA (0.44) | NAAASMN1; SMN2CYP19A1HTTEPHX1 | |
| SCHEMBL231985 | 0.90 | NAAA (0.45) | NAAASMN1; SMN2CYP19A1HTTEPHX1 | |
| SCHEMBL13662184 | 0.82 | NAAA (0.46) | NAAASMN1; SMN2CYP19A1HTTEPHX1 | |
| SCHEMBL6878693 | 0.80 | NAAA (0.39) | NAAASMN1; SMN2CYP19A1EPHX1LMNA | |
| SCHEMBL20207259 | 0.80 | NAAA (0.49) | NAAACYP19A1HTTEPHX1CYP2C19 | |
| SCHEMBL12744578 | 0.79 | NAAA (0.41) | NAAASMN1; SMN2CYP19A1HTTEPHX1 | |
| SCHEMBL13647263 | 0.76 | CYP19A1 (0.41) | NAAASMN1; SMN2CYP19A1HTTEPHX1 | |
| Hydrochloric Acid SCHEMBL6873846 | 0.76 | LMNA (0.39) | SMN1; SMN2LMNA | |
| SCHEMBL14504409 | 0.76 | MMP1 (0.41) | NAAASMN1; SMN2CYP19A1HTTEPHX1 | |
| SCHEMBL28499766 | 0.75 | NAAA (0.42) | NAAACYP19A1HTTEPHX1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463713-A1 | PRODRUGS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003045898-A1 | PRODRUGS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-06-05 | — | — | WO | disclosed |