Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878792 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2GAARAB9ANPC1POLB | |
| SCHEMBL6879741 | 0.94 | SMN1; SMN2 (0.39) | SMN1; SMN2GAARAB9ANPC1POLB | |
| SCHEMBL6879728 | 0.94 | SMN1; SMN2 (0.39) | SMN1; SMN2GAARAB9ANPC1POLB | |
| SCHEMBL6879736 | 0.94 | SMN1; SMN2 (0.39) | SMN1; SMN2GAARAB9ANPC1POLB | |
| SCHEMBL6879250 | 0.92 | RAB9A (0.44) | SMN1; SMN2GAARAB9ANPC1POLB | |
| SCHEMBL6879246 | 0.92 | RAB9A (0.44) | SMN1; SMN2GAARAB9ANPC1POLB | |
| SCHEMBL6878845 | 0.92 | SMN1; SMN2 (0.52) | SMN1; SMN2GAARAB9ANPC1POLB | |
| SCHEMBL6878840 | 0.92 | SMN1; SMN2 (0.52) | SMN1; SMN2GAARAB9ANPC1POLB | |
| SCHEMBL6876383 | 0.91 | SMN1; SMN2 (0.51) | SMN1; SMN2GAARAB9ANPC1POLB | |
| SCHEMBL6456286 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2GAARAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |