Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879250 | 1.00 | RAB9A (0.44) | RAB9AGAAPOLBALDH1A1MAPK1 | |
| SCHEMBL6878795 | 0.92 | SMN1; SMN2 (0.43) | RAB9AGAAPOLBALDH1A1MAPK1 | |
| SCHEMBL6878792 | 0.92 | SMN1; SMN2 (0.43) | RAB9AGAAPOLBALDH1A1MAPK1 | |
| SCHEMBL6875449 | 0.91 | ALDH1A1 (0.45) | RAB9AGAAPOLBALDH1A1KMT2A | |
| SCHEMBL6875441 | 0.91 | ALDH1A1 (0.45) | RAB9AGAAPOLBALDH1A1KMT2A | |
| SCHEMBL6878845 | 0.89 | SMN1; SMN2 (0.52) | RAB9AGAAPOLBALDH1A1KMT2A | |
| SCHEMBL6878840 | 0.89 | SMN1; SMN2 (0.52) | RAB9AGAAPOLBALDH1A1KMT2A | |
| SCHEMBL6456286 | 0.88 | SMN1; SMN2 (0.41) | RAB9AGAAPOLBALDH1A1MAPK1 | |
| SCHEMBL6868508 | 0.88 | NPSR1 (0.50) | RAB9AGAAPOLBALDH1A1MAPT | |
| SCHEMBL6456275 | 0.88 | SMN1; SMN2 (0.41) | RAB9AGAAPOLBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |